Endocrine Abstracts

Bronchial carcinoid tumours are uncommon pulmonary neoplasms. Manifestation of a bronchial carcinoid with acromegaly secondary to extra-pituitary growth hormone releasing hormone (GHRH) production is rare, but bronchial carcinoid tumours are the most common cause of ectopic GHRH secretion.We report the case of 60 year old female, ex-smoker with hypertension presenting with cough, dyspnoea and right lower lobe opacity on the chest X-ray. Patient was noted...

Vasopressin receptor 2 antagonist (V2RA) provide treatment option for patients with hyponatraeamia in the context of syndrome of inappropriate antidiuretic hormone secretion (SIADH).We report the results of seven patients (six males, one female, average age 65.7) with hyponatraemia secondary to SIADH treated with V2RA (Tolvaptan) in years 2011–2013. Six patients had underlying diagnosis of lung cancer, one patient was diagnosed with sarcoidosis. Fou...

The prevalence of the type 2 diabetes and obesity are on the rise globally. Initial interventions for these groups of patients remain diet, exercise and medications. If these measures are insufficient gastrointestinal surgery offers a very good alternative for obesity and type 2 diabetes treatment.We report the outcome results for patients who underwent either adjustable gastric banding (AGB) or Roux-en-Y (RNY) gastric bypass in the years 2009–2012....

The prevalence of the type 2 diabetes and obesity are on the rise globally. Initial interventions for these groups of patients remain diet, exercise and medications. If these measures are insufficient gastrointestinal surgery offers a very good alternative for obesity and type 2 diabetes treatment.We report the outcome results for patients who underwent either adjustable gastric banding (AGB) or Roux-en-Y (RNY) gastric bypass in the years 2009–2012....

Background: Intramuscular long acting testosterone injections are widely used, convenient form of androgen replacement in patients with hypogonadism.Aims: To evaluate the long term effects of parenteral long acting testosterone replacement on patients commenced on treatment in years 2006–2014 and adherence to monitoring undertaken by primary care after discharge from specialist service.Method: We reviewed the results of 64 pat...

Patients with primary hyperparathyroidism (PHPT) undergo parathyroid ultrasound, Tc-99m sestamibi scan or MRI to localize hyperfunctioning parathyroid gland(s). When scans are negative or discordant we perform parathyroid hormone selective venous sampling (PTHSVS).We report the results of 18 patients (four males, 14 females, average age 58.7) with PHPT, who underwent PTHSVS followed by either focused parathyroidectomy (FP) or bilateral neck exploration (...

Patients with primary hyperparathyroidism (PHPT) undergo parathyroid ultrasound, Tc-99 m sestamibi scan or MRI to localize hyperfunctioning parathyroid gland(s). When scans are negative or discordant we perform parathyroid hormone selective venous sampling (PTHSVS).We report the results of 17 patients (Four males, 13 females, average age 58.6) with PHPT, who underwent PTHSVS followed by either focused parathyroidectomy (FP) or bilateral neck exploration ...

Although TIH is a well-established complication of this drug class, the extent of this problem and the serious morbidity that can result is often not appreciated. At our centre, we became aware of three serious cases of TIH over a 2-week period during the ‘heat wave’ in July 2013. In at least one of these cases excessive water drinking was a clear precipitant. We therefore determined the incidence of TIH at our hospital and in particular whether there is a seasonal e...

In patients with diabetes an isolated ‘sausage toe’ is suggestive of underlying osteomyelitis. Neuropathic (Charcot) arthropathy, devastating complication of diabetes, normally presents in the midfoot and can be precipitated by surgery or minor trauma.We report a 62-year-old man with a 2-year history of well controlled type 2 diabetes (HbA1c 56 mmol/mol), with no micro or macro vascular complications, referred to diabetic podiatrist with a hot,...